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Implementation research


Precision psychiatry has developed into a combined area of clinical research, with many individualised prediction models developed and validated on data from more than 3 million participants aged from 1 to 64 years.

There are many validated individualised prediction models available. These can target multiple psychiatric conditions covering psychotic disorders, affective disorders, substance use disorders, anxiety disorders, neurodevelopmental disorders and several clinically relevant outcomes as well.

Despite the progress we’ve seen in developing and validating individualised prediction models for psychiatry, there are some important barriers to the advancement of knowledge.

  • The first barrier is that across the overall pool of prediction models developed and published in the broader psychiatric literature, only about 15% is properly validated (10% internal validation and 5% independent external validation).
  • The second barrier is that the proportion of prediction models developed and published in psychiatry, only 0.2% is then implemented in clinical routine.

Our Prediction Modelling Group provides innovative approaches to tackle this translational gap and advance implementation science.

Our group is collaborating with other international initiatives such as the European College of Neuropsychopharmacology Network for the Prevention of Mental Disorders and Mental Health Promotion (ECNP PMD-MHP) and the European Brain Area Research Area (EBRA) to develop a coherent and global implementation framework, methodological infrastructures and international implementation infrastructures.

For more information, please contact Dr Paolo Fusar-Poli, Reader of Youth Mental Health at paolo.fusar-poli@kcl.ac.uk.

Prediction Modelling Group

Prediction Modelling Group

Our Prediction Modelling Group provides a forum for researchers, clinicians and other experts.
About precision medicine and prediction modelling

About precision medicine and prediction modelling

Precision medicine is an emerging approach that focuses on identifying treatments or approaches.
Initiatives and aims

Initiatives and aims

We are finding prediction modelling researchers to establish an online database listing members’ areas of interest and expertise.
People

People

Meet the current members of the group and discover their areas of interest.
Join our prediction modelling group

Join our prediction modelling group

Joining our group helps create our database of researchers and establish collaborations within our institution and beyond.
Prediction Modelling Workshop

Prediction Modelling Workshop

Videos from the inaugural workshop of our Prediction Modelling Group including presentations from world-renowned experts.
Prediction Modelling Presentations

Prediction Modelling Presentations

Our Prediction Modelling group will be hosting regular presentations to engage and introduce new members to our community.
Ethics

Ethics

Predictive models that use data from individuals are an important source of information in medical settings.